Nisong Monyimba
Biomedical engineering
Hometown: Accra, Greater Accra Region, Ghana
Graduation date: Spring 2022
Additional details: First-generation college student
![Nisong Monyimba](https://stg-furi.fsewp.asu.edu/wp-content/uploads/2022/03/TF56P5WNL-U01DQ8FTVT4-ee6e78d0ff7e-512.jpg)
MORE | Spring 2022
Trophoblast-On-Chip Model
The maternal-fetal interface is challenging to investigate in in vivo models due to species-specific differences in placental development and ethics evaluating placental development in humans during gestation. The research team aims to develop a 3D placental microfluidic culture system (trophoblast-on-a-chip model) to mimic the human placental microenvironment by reproducing key placental microenvironment elements such as trophoblast cells and pancreatic extracellular matrix (ECM) components. The research team designed a 3D printed chip that incorporates dynamic medium flow, with the goal of enabling real-time monitoring of trophoblast cell invasion and cell-to-cell interactions. The team is currently evaluating the suitability of our chip design as a platform to support ECM-mimicking hydrogels and trophoblast cell viability.
Mentor: Jessica Weaver