Jennifer Lynn Brodsky

Biomedical engineering

Hometown: Surprise, Arizona, United States

Graduation date: Spring 2021

Health icon, disabled. A red heart with a cardiac rhythm running through it.

FURI | Summer 2020

Phage Assisted Continuous Evolution (PACE) with PhiX174

Phage assisted continuous evolution (PACE) is the most current and advanced method of protein engineering, allowing for accelerated development and complex functions. The research team sought to explore opportunities for PACE with a new phage, PhiX174 and new mechanisms of positive and negative selection. For positive selection, Gene H was chosen because previous literature shows phage viability depends on relative expression levels. A negative selector of MbcT/MbcA was chosen, which counters NAD+ phosphorylation, an essential cofactor for metabolism. The combination of these selectors and our phage will allow for researchers an open access to methods of directed evolution.


View the poster
QR code for the current page

It’s hip to be square.

Students presenting projects at the Fulton Forge Student Research Expo are encouraged to download this personal QR code and include it within your poster. This allows expo attendees to explore more about your project and about you in the future. 

Right click the image to save it to your computer.