Era Joy Padilla Agus

Biomedical engineering

Hometown: Quezon City, National Capital Region, Philippines

Graduation date: Spring 2024

Additional details: Honors student

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GCSP research stipend | Spring 2024

Nano Contrast Agents in Photoacoustic Imaging: In Vitro and Ex Vivo Insights

This study investigates using indocyanine green (ICG) and locked nucleic acid-indocyanine green (LNA-ICG) as contrast agents in photoacoustic imaging. In vitro analysis involves imaging ICG and LNA ICG samples in sample tubes that are immersed in either water or embedded in agarose gel. Ex vivo analysis involves injection of LNA-ICG into a rat brain, then fixing the brain in agarose for imaging. Results suggest that LNA-ICG can effectively serve as a contrast agent for imaging of biological tissue, demonstrating potential for minimally invasive, high-contrast visualization in photoacoustic imaging. This research provides insights into optimizing photoacoustic imaging techniques.

Mentor:

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Additional projects from this student

Improving preclinical neuroimaging will enable more accurate diagnoses and personalized treatment of neurological diseases.

Mentor:

  • FURI
  • Fall 2023

Determining the most efficient design for thermal regulation in bioreactors will enable a sustainable way to carry antibiotics for space travel.

Mentor:

  • FURI
  • Fall 2022