FURI | Spring 2018

Adaptation of Laser Activated Sutures for Intestinal Surgeries via Chemical Cross-linking

This project seeks to adapt previously developed laser-activated sutures for use in intestinal surgeries. Previous work in this area developed laser activated sutures that improve wound healing by providing an immediate seal upon activation with a near-infrared laser. This project will help address the issue of common, life threatening complications involving intestinal surgeries due to the absence of such a seal. The current aim of this research is to improve the mechanical strength of previously developed laser-activated sutures under wet conditions through chemical cross-linking. Future work will include optimization of cross-linking parameters, and in-vivo testing in mouse models.